October 8, 2025

Top Questions Patients Ask About Joint Injections

Image of physician performing ultrasound-guided joint injection



Joint pain is a common complaint as we age or due to injuries, arthritis, or inflammation. When over-the-counter pain relievers and physical therapy aren’t enough, joint injections become an important option. These injections deliver medication directly into the joint to reduce inflammation and pain, helping you regain mobility and comfort.

If you’ve been recommended a joint injection or are exploring treatments for joint pain, you probably have many questions. What exactly happens during the injection? Is it safe? How long will the relief last? What are the risks and benefits? This blog post answers the top questions patients ask about joint injections, with clear, empathetic explanations tailored for readers aged 30 to 60 who want to understand their treatment options better.

We’ll guide you through the basics, causes and risk factors of joint issues, what to expect from joint injections, practical tips, and frequently asked questions—all based on the latest medical evidence and guidelines.

What Are Joint Injections?

Joint injections are treatments where medication is injected directly into a joint to relieve pain and inflammation. The most common joints treated are the knee, shoulder, hip, and smaller joints like fingers or toes.

The medications used include:

  • Corticosteroids (steroids) to reduce inflammation quickly
  • Local anesthetics to numb the area and provide immediate pain relief
  • Hyaluronic acid to lubricate joints in osteoarthritis
  • Platelet-rich plasma (PRP) or stem cell treatments in some cases (still under study)

These injections target the joint space, where inflammation or damage causes pain and swelling. By delivering medicine directly there, joint injections can provide faster and more effective relief than oral medications.

Why Do People Need Joint Injections?

Joint injections are usually recommended when:

  • You have arthritis (osteoarthritis or inflammatory arthritis like rheumatoid arthritis) causing joint pain and swelling
  • Conservative treatments like medication, exercise, or physical therapy haven’t provided adequate relief
  • You have a joint flare or acute inflammation worsening symptoms suddenly
  • There is fluid buildup (effusion) in the joint causing discomfort and stiffness
  • You need help to improve joint mobility for daily activities

These injections are not a cure but a tool to manage symptoms, improve function, and delay the need for surgery like joint replacement, especially in early to moderate arthritis.

Causes and Risk Factors for Joint Pain Treated by Injections

Joint pain can arise from several conditions:

  • Osteoarthritis (OA): A degenerative joint disease causing cartilage breakdown and joint inflammation
  • Rheumatoid arthritis (RA): An autoimmune disease causing joint inflammation and damage
  • Bursitis or tendonitis near joints causing pain and swelling
  • Injuries or trauma causing joint inflammation
  • Gout or pseudogout leading to crystal-induced inflammation inside joints
  • Overuse or repetitive strain causing joint irritation

Risk factors increasing joint pain include aging, obesity, joint injuries, genetics, autoimmune disorders, and mechanical stress.

What to Expect During a Joint Injection Procedure

If you’re nervous about joint injections, here’s what usually happens:

  1. Assessment and consent: Your doctor examines the joint, discusses benefits and risks, and answers your questions before you consent
  2. Preparation: The skin over the joint is cleaned with antiseptics to prevent infection
  3. Guided injection: In many cases, ultrasound or X-ray helps guide the needle precisely into the joint, improving accuracy and safety
  4. Injection: A combination of steroid and local anesthetic is injected; sometimes fluid is removed first if the joint is swollen
  5. Post-procedure care: A bandage is applied, and you’re advised to rest the joint for 24–48 hours

Many patients experience immediate numbness from the anesthetic, followed by temporary soreness that usually goes away within a few days.

How Long Does Relief Last?

Relief duration varies widely depending on the medication used, the joint treated, and individual patient factors:

  • Corticosteroid injections typically provide relief lasting from a few weeks up to 3 months
  • Hyaluronic acid injections may offer longer-lasting lubrication effects in osteoarthritis but evidence varies
  • Relief from injections is usually temporary; repeated injections may be needed, but with limits to avoid tissue damage

Benefits of Joint Injections

  • Rapid and targeted reduction of joint pain and swelling
  • Improved mobility and function in daily life
  • Potential to delay or reduce need for surgery
  • Minimally invasive with quick recovery time

Risks and Potential Side Effects

Joint injections are generally safe but have some risks including:

  • Temporary flare of pain and swelling around the injection site
  • Infection (rare)
  • Allergic reactions to medications
  • Possible cartilage damage or weakening of tendons with repeated steroid use
  • Elevated blood sugar temporarily in diabetics after steroids

Careful patient selection, sterile technique, and image guidance minimize risks. Your doctor will discuss these before the procedure.

Practical Tips Before and After Injection

Practical Tips Before and After Injection

  • Inform your doctor about allergies, infections, and blood-thinning medications
  • Arrange for a ride home if sedation or strong pain relief is used
  • Avoid strenuous activity for 1–2 days post-injection
  • Use ice and over-the-counter pain relievers as needed for soreness
  • Contact your doctor if you develop significant redness, swelling, fever, or worsening pain

FAQs About Joint Injections

1. Does the injection hurt?

Most patients experience mild discomfort during the injection. A numbing spray or local anesthetic helps reduce pain.

2. How many injections can I get?

Doctors generally limit steroid injections to 3–4 per year in the same joint to avoid damage.

3. Can joint injections cause infection?

The risk is very low (less than 1%) if sterile technique is followed.

4. Are injections safe if I have diabetes?

Steroid injections can temporarily raise blood sugar. Monitoring is important, but risks can be managed.

5. What if the injection doesn’t work?

Alternatives like physical therapy, oral medications, or surgery may be considered.

6. Can injections reverse arthritis?

No, injections manage symptoms; they don’t cure or reverse joint damage.

7. Is image guidance necessary?

Guidance with ultrasound or X-ray improves accuracy and may enhance outcomes.

Key Takeaways

  • Joint injections are a safe, effective way to reduce pain and inflammation in many joint conditions
  • The procedure involves delivering medications like steroids directly into the joint under sterile conditions
  • Relief is often temporary but can improve quality of life and delay surgery
  • Risks are low but include infection and potential joint damage with repeated injections
  • Patients should discuss benefits, risks, and expectations thoroughly with their healthcare provider

Conclusion

If joint pain is limiting your daily activities, joint injections could be a valuable option to gain relief and improve function. Understanding what to expect and feeling confident in your treatment plan helps you make informed decisions for your health.

If considering a joint injection, talk to your physician about whether it’s right for your condition and ask any questions you have. Together, you can develop a plan that fits your lifestyle and health goals.

Take control of your joint health and explore how targeted injections can help reduce pain and get you moving comfortably again.

References

  1. Brinks A, et al. Use and safety of corticosteroid injections in joints and soft tissues: A clinical guideline. Reg Anesth Pain Med. 2025 Mar 11. PubMed
  2. Johns Hopkins Rheumatology. Joint Injections 101. 2020. Hopkins
  3. Guermazi A, et al. Steroid injections of hip and knee may damage joints. Radiology. 2019 Oct 14. RSNA
  4. Mayo Clinic. Cortisone shots. 2023. MayoClinic
  5. Fernandes L, et al. EULAR recommendations for intra-articular therapies. Ann Rheum Dis. 2021 May 24. PMC

Disclaimer: This article is for informational purposes only and should not replace professional medical advice. Always consult your doctor before starting or changing any treatment for joint pain.

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